If you start a new game plus save after finishing the game once, you’ll have to pick up all treasures again, so you can restart your search then. The only thing to note is that, once you cross the point of no return of a region, you won’t be able to go back and grab any treasures you’ve missed - unless you made a manual save beforehand. You can open them in any order, and there isn’t a specific key for a specific drawer. How to open locked drawers in Resident Evil 4 remakeįor every locked drawer you find in the Resident Evil 4 remake, there is a Small Key for it hidden somewhere in the region. If you’re curious about what each locked drawer has trapped inside, you can find each reward and its worth in the last section. Regardless of whether you’re looking to complete the merchant’s treasure maps in the Resident Evil 4 remake or just want to make bank, below are all Small Key locations scattered in the game. If you’ve stumbled upon a locked drawer, that means there is a treasure waiting to be picked up inside. Some are locked behind puzzles, but others require Small Keys in order to retrieve them. The Resident Evil 4 remake has no shortage of treasures to hunt in each of its three main regions.